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KMID : 0363620180390010095
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Journal of Korean Oriental Medicine
2018 Volume.39 No. 1 p.95 ~ p.103
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Anti-hypertensive effect by Single adminstration of Chunghyul-dan : A CASE SERIES
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Moon Sang-Kwan
Kim Su-Bin
Kwon Seung-Won
Cho Seung-Yeon
Park Sung-Wook
Jung Woo-Sang
Park Jung-Mi
Ko Chang-Nam
Cho Ki-Ho
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Abstract
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Objectives: This study was designed to investigate antihypertensive effect by single adminstration of Chunghyul-dan in stroke patients.
Methods: This is a 31-patient case series from retrospective chart review of inpatients who diagnosed with stroke at a Kyung Hee University Korean Medicine Hospital (Seoul) between October 2016 to October 2017. We reviewed patient’s charts with transient and sudden increases in blood pressure who were treated with Chunghyul-dan and analyzed blood pressure over time. In addition we classified patients by using the standardized predictive models for Korean medical diagnostic pattern-identification to find out if there are some differences in responder ratios.
Results: Thirty one patients who took Chunghyul-dan were identified. 60 minutes, 120 minutes after 1200mg administration, systolic and diastolic blood pressure decreased significantly compared to baseline. We could not identify the difference between the groups of each pattern-identification because of small number of some groups.
Conclusions: Although limited by its retrospective nature, this study suggests that Chunghyul-dan may be effective as short term antihypertensive method for stroke patient.
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KEYWORD
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Chunghyul-dan, Hypertension, Stroke, Diagnostic Pattern identification, Antihypertensive effect
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